Do you remember yesterday's story about the luminous bacterium Vibrio fischeri and the Hawaiian squid Euprymna scolopes, without which the latter can not exist? How do microbes form animal organisms? This ability is based on 2 molecules. Earlier they were known in the context of pathologies. They were referred to pathogen-associated molecular patterns (PAMRs). These are substances that alert the animal's immune system about infection. But after all, Vibrio fischeri is not a pathogen! She is necessary for a squid! And the "pathogenic" P is interchangeable with the "microbial" M! The new term, like the hymns, is very symbolic. Such a change tells the world that these molecules are not only a sign of disease!